Leukimia Mielositik Kronis [PDF]

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Leukimia Mielositik Kronis (oleh: Priska Pramuji)



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Diagnosis Banding (berdasarkan neoplastik mieoloproliferasi): 1. CML 2. Polisitemia Vera 3. Essential thrombocythemia No. Indikator CML Trombositosis esensial 1.



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Polisitemia Vera



40-50th



>50th 39%:61%



40-60 thn 2:1



2.



Epidemiology a. usia b. gender (L:P) Splenomegaly



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+



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3.



Berkeringat malam



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-



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4.



Leukositosis



bervariasi



+ basofilia



5. 6. 7.



Trombositosis Anemia Sel granulosit perifer



+ neutrof ilia + + +



++ bervariasi -



+ ringan -



8.



Sel Blast 50 × 109/L, range 20 to >500 × 109/L) Full spectrum of granulocytes and precursors with rare blasts 10:1) with spectrum similar to blood Characteristic small, hypolobated megakaryocytes Blasts